![]() ![]() RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer.Research Activities 2022-2023 Vol.1 released - Eight Latest Research Activities from TMDU.Preferential delivery of lipid-ligand conjugated DNA/RNA heteroduplex oligonucleotide to ischemic brain in hyperacute stage.Analysis of swallowing function after anterior/posterior surgery for cervical degenerative disorders and factors related to the occurrence of postoperative dysphagia.Enteral liquid ventilation oxygenates a hypoxic pig model.Regarding the AY 2023 Tokyo Medical and Dental University Entrance Ceremony for Undergraduate and Graduate Students.Effects of tongue right positioner use on tongue pressure: a pilot study.Research Activities 2022-2023 Vol.2 released - Eight Latest Research Activities from TMDU.Enteral ventilation pathway offers an effective means for systemic oxygenation, thus warranting further clinical development. SvO 2 dynamic monitoring data indicated that oxygenation likely originated from the venous outflow of the broad segment of large intestine including the inferior mesenteric vein route. Early oxygen transfer dynamics inversely correlate with baseline oxygenation status. Intrarectal O 2-PFD administration significantly increased the partial pressure of oxygen in arterial blood from 54.5 ± 6.4 to 61.1 ± 6.2 mmHg (mean ± SD) and reduced the partial pressure of carbon dioxide from 38.0 ± 5.6 to 34.4 ± 5.9 mmHg. We simultaneously monitored arterial and pulmonary arterial blood gases every 2 min up to 30 min to determine the gut-mediated systemic and venous oxygenation kinetics. 20 mL/kg of oxygenated perfluorodecalin (O 2-PFD) was intra-anally delivered by a rectal tube. ![]() Here, we assessed the enteral ventilation approach in hypoxic porcine models under controlled mechanical ventilation. The potential of extrapulmonary ventilation pathways remains largely unexplored. ![]()
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