Mentor junior scientists' activities and provide technical guidance when necessary.Conduct and implement in vitro transcription assay to produces high-quality RNA and develop/perform analytic assay for RNA quality evaluation.Work in a dynamic background team to contribute to the development of RNA stabilization for immunization.Perform RT-qPCR/ddPCR, western blot, immunofluorescence assay to evaluate RNA vaccine candidates, and to investigate/understand the mechanism for next generation RNA vaccine candidates.Combine expertise in molecular biology, synthetic biology, nucleic acid chemistry, and virology techniques to help build an efficient pathway to convert virus sequence data into RNA vaccine constructs, and synthetic related viruses.The incumbent will work closely with the group leader, project teams, supporting lines and team members to drive the design and execution of in vitro studies, and take a "hands on" role to support laboratory activities. The incumbent will apply molecular and biochemical techniques to support RNA based vaccine program and other viral research programs in the Viral Vaccines group. The incumbent should possess a strong scientific curiosity and rigor and a strong background in molecular biology and RNA virology research. The use of viral molecular and synthetic technologies will also support production of candidate RNA constructs and viruses for pre-pandemic and pandemic vaccine development. The successful applicant will play a fundamental role in developing and implementing an innovative molecular strategy for rapid and accurate generation of DNA templates for RNA production and related virus rescue. The Viral Vaccines group is seeking an experienced lab-based molecular virologist to support development of RNA-based viral vaccines. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Pfizer's purpose is to deliver breakthroughs that change patients' lives.
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